I could see that the talk of divorce was causing her some discomfort.

discomfort 是由前缀 dis-（表示"否定、相反"）和名词 comfort（"舒适"）组成的名词，字面意思是"不舒适"。这个词指身体或心理上的不适感，程度比 pain（疼痛）要轻。