老板为这个项目提供了详细的指示。

The boss provided detailed ___instructions for the project.

她留下了具体的指示，包裹在她到达之前不得打开。

She left specific ___instructions that the package should not be opened until her arrival.

在实验室中，遵守安全指示是强制性的。

Adhering to the safety ___instructions is mandatory in the laboratory.