她的离开对研究团队来说将是一个重大的损失。

Her departure would be a significant ___loss to the research team.

他的退休对该组织来说将是一个巨大的损失。

His retirement will be a considerable ___loss for the organization.

关键经理的辞职对公司来说是一个重大损失。

The resignation of the key manager was a major ___loss to the company.