医生们为挽救病人的生命做了最后一次绝望的尝试。

The doctors made one last ___desperate attempt to save the patient's life.

他们发出了绝望的求助呼吁。

They made a ___desperate appeal for help.

失业后，他感到真正的绝望。

After losing his job, he felt truly ___desperate.