她充满了深深的绝望感。

She was filled with a deep sense of ___despair.

他们因失去的钱财而陷入绝望的深渊。

They're in the depths of ___despair over the money they've lost.

几乎绝望地，我走出浴室，尽力寻找一支蜡烛。

Almost in ___despair, I came out of the bathroom and tried my best to look for a candle.