有缺陷的部件导致整个机器故障。

The ___defective part caused the whole machine to fail.

大楼有缺陷的线路构成了严重的火灾隐患。

The building's ___defective wiring posed a serious fire hazard.

由于一个有缺陷的基因，这种疾病被遗传了。

Due to a ___defective gene, the condition was inherited.