尽管消息令人震惊，但没有人放弃希望。

Despite the ___devastating news, no one is giving up hope.

对于这样的人来说，经历这种事情可能真的令人震惊。

It can be really ___devastating for such a person to experience it.

她毁灭性的评论让他感到非常沮丧。

Her ___devastating comments left him feeling deeply upset.