当你穷困潦倒时，没有人会爱你。

Nobody loves you when you're ___down ___and ___out.

社会忽视可能使人陷入绝境，几乎无望改善。

Social neglect can leave people ___down ___and ___out, with little hope for improvement.

失去工作和积蓄后，他发现自己彻底一无所有、走投无路。

After losing his job and savings, he found himself completely ___down ___and ___out.