她以成为锦标赛有史以来最年轻冠军为目标开始了征程。

She ___set ___out with the aim of becoming the youngest ever winner of the championship.

他们以发现癌症治疗方法为目标开始了研究。

They ___set ___out to discover a cure for cancer.

这就是为什么在她儿子被命名为皇帝的那一天，她的嘴角挂着一丝满意的微笑，因为她至少实现了她最初的目标，那就是让她的儿子登上王位。

That is why the day her son was named emperor a smile of satisfaction played round her lips, because at least she had achieved what she had ___set ___out to do, which was make her son ascend the throne.