该国与世界经济上的隔离阻碍了其发展。

The country's economic ___isolation from the rest of the world has hindered its development.

由于其地理隔离，这个国家不得不自给自足。

Due to its geographic ___isolation, the nation had to become self-sufficient.

社交隔离可能对心理健康产生有害影响。

Social ___isolation can have detrimental effects on mental well-being.