It seems to me that she's in the wrong job.

it 在这里是形式主语，指代后面that引导的从句内容。 seems 是动词 seem 的第三人称单数现在时形式，意思是"看起来、似乎"，表示说话者的主观判断。 it seems to me 是一个固定表达，意思是"在我看来"，用于表达个人观点。