It was so unfortunate that she lost her job just as her husband became ill.

unfortunate 是由前缀 un-（表示“不”）和形容词 fortunate（幸运的）组成的形容词。fortunate 来自名词 fortune（运气、财富），所以 unfortunate 的字面意思是“不幸运的”，即“不幸的”。