他因放弃责任而感到压倒性的负罪感。

He felt overwhelming ___guilt for abandoning his responsibilities.

通过承认负罪感，他寻求家人的原谅。

By admitting his ___guilt, he sought forgiveness from his family.

没有帮助她的负罪感困扰了他多年。

The ___guilt of not helping her haunted him for years.