总的来说，人们对这些变化表示欢迎。

___By ___and ___large, people have welcomed the changes.

大体而言，当今旅游业利大于弊。

___By ___and ___large, tourism is more beneficial than harmful today.

总体来看，这座城市的生活质量相当高。

___By ___and ___large, the quality of life in this city is quite high.