His self-centered attitude made it difficult for others to work with him.

self-centered 是由 self（自己）和 centered（以...为中心的）组成的复合形容词。self 表示"自我"，centered 来自动词 center（使集中），加上 -ed 变成形容词，表示"以...为中心的"。 self-centered 意思是"以自我为中心的"，形容一个人只关心自己的利益和需求，不考虑他人感受。