你再问他也没用，他还是会拒绝。

It ___makes ___no ___difference if you ask him again; he'll still say no.

你把天线放在哪里都没关系，电视画面还是不好。

It ___makes ___no ___difference where you put the aerial; the TV picture is still bad.

走哪条路有区别吗？

Does it ___make ___any ___difference which route we take?