尽管遇到挫折，不要灰心；成功往往在坚持之后到来。

Despite the setbacks, don't ___lose ___heart; success often comes after persistence.

我们必须学会克服障碍，永不丧失信心。

We must learn to overcome obstacles and never ___lose ___heart.

在多次被拒绝后，他开始灰心并考虑放弃。

After repeated rejections, he began to ___lose ___heart and consider giving up.