他在那次严肃的会议上开了那个玩笑，真是搞砸了。

He really ___blew ___it when he made that joke during the serious meeting.

由于错过了截止日期，她失去了晋升的机会。

By missing the deadline, she ___blew ___her ___chances of getting the promotion.

这是你达成交易的最终机会——可别搞砸了。

This is your final opportunity to close the deal - don't ___blow ___it.